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      <image:title>Blog - Dose Selection in Proof-of-Concept Trials: When to use a single “no regret” dose versus multi-dose evaluation - Make it stand out</image:title>
      <image:caption>This aligns with guidance from the FDA and industry practice recommending evaluation of a range of doses during development and justifying dose selections with exposure-response evidence (5,6,12) . The oncology literature also strongly supports early dose optimization rather than reliance on MTD alone (9–11) .</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Blog - Dose Matters: Navigating FDA Guidance for Oncology Drug Development&amp;nbsp; - Make it stand out</image:title>
      <image:caption>Figure 1 - Typical relationships between drug exposure and the likelihood of a tumour response and dose-limiting toxicity [2]. MTD: Maximum Tolerated Dose.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Blog - Dose Matters: Navigating FDA Guidance for Oncology Drug Development&amp;nbsp; - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Home - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Home - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Home - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Home - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Services - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/275776c9-9767-4f06-bf56-40b268447151/Macaro%2C+Debbie.jpg</image:loc>
      <image:title>Case studies - “Implementing a robust quality management system.”</image:title>
      <image:caption>Debbie Macaro, Clinical Operations Director</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/0576cae2-3257-4aa4-a1ff-7f53ab56ff4e/McHale%2C+D2.jpg</image:loc>
      <image:title>Case studies - “Novel protocol design for early insights into patient data.”</image:title>
      <image:caption>Dr Duncan McHale, Co-Founder and Drug Development Expert</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/14a0b1e7-c840-409d-9ab3-877b4e2c1272/Wydenbach%2C+K2.jpg</image:loc>
      <image:title>Case studies - “Navigating regulatory requirements for rare diseases and securing priority review.”</image:title>
      <image:caption>Dr Kirsty Wydenbach, Head of Regulatory Strategy</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/f47d8068-f765-431a-9beb-839d72c56591/Tinsley%2C+E2.jpg</image:loc>
      <image:title>Case studies - “Capital efficient company creation opportunity.”</image:title>
      <image:caption>Emma Tinsley, CEO</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1632012600389-HOZDIAMKC51YLR4L5DLK/a+70c-w.png</image:loc>
      <image:title>Case studies</image:title>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1632012616619-E3AGK9OJPM90ZKOGRR76/b+200m-w.png</image:loc>
      <image:title>Case studies</image:title>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1632012638542-MJ828VK39TOTO1FCCVV9/c+13b-w.png</image:loc>
      <image:title>Case studies</image:title>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1631999013173-0TXLXUNQE7D9A9UEWI7D/a+Client+sat.png</image:loc>
      <image:title>Case studies - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1631999086900-BN1FN6WWUC2SE8TB9E8V/b+Clin+successes.png</image:loc>
      <image:title>Case studies - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1631999110647-HZY5LO47QNRSOKGPKB3L/c+500.png</image:loc>
      <image:title>Case studies - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1631999126185-FLTGILNH120I823005UC/d+Intl+reach.png</image:loc>
      <image:title>Case studies - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1631999145293-3QFJ3LMSY8VBSU4TS6S7/e+Regulatory+win.png</image:loc>
      <image:title>Case studies - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/6145bc4a7225635f6aee59ba/1631999161720-W2STWW4GW9CYPBBJTSGY/f+Therapeutic+areas.png</image:loc>
      <image:title>Case studies - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
  </url>
</urlset>

